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ネクセラファーマ(株)【4565】の掲示板 2017/06/17〜2017/06/21

※HeptaresTL: We are currently seeking an experienced Bioinformatician GPCR. (6/1up)
※"Bioinformatician"
・Company: Heptares Therapeutics
・Published:29-May-2017
・The closing date for applications is 5th July 2017.

※HeptaresTL 7時間前: We are now seeking to recruit a highly motivated Bioinformatician GPCR. (6/16Re-update)
※"Bioinformatician"
Company: Heptares Therapeutics
Published:13-Jun-2017

Heptares Therapeutics is clinical stage company using innovative techniques in protein engineering and structure based drug design directed at G protein-coupled receptors (GPCRs).
Heptares has built an exciting pipeline of new medicines across disease areas including Alzheimer’s disease, migraine and cancer.
Our ability to address highly validated, yet historically undruggable, GPCRs has also attracted multiple partners including Allergan, AstraZeneca, Daiichi Sankyo, Kymab, Morphosys, Pfizer and Teva.

We are currently seeking an experienced Bioinformatician to work with scientists internally and externally across a range of disciplines to advance both our platform technology and our pipeline of new medicines.

Our preferred candidate would have the following background:
・Educated to PhD level in Biochemistry or a related Biomedical science, with experience in applying Bioinformatics approaches to Biomedical questions
・Expertise in R programming and Python scripting
・A solid understanding of protein families, their physiological functions and their regulation by endogenous and exogenous ligands
・Broad knowledge of 3D structures of proteins and ligands
・Experience with the development and application of informatics approaches to analyse databases (including protein sequences and structures)
・Familiarity with integrated sequence/structure/small molecule approaches and databases (e.g. ChEMBL)
・Experience of working in a drug discovery environment would be an advantage

The successful candidate will work independently but in association with other Heptares functions to:
・Mine databases, publications and other sources of information to help generate disease/protein associations and identify suitable targets for drug discovery
・Assist with the assessment of opportunities for new projects involving novel targets and/or novel drug molecules
・Work with selected academic partners to use informatics data to progress target validation and drug discovery projects
・Examine the effects of sequence variation on the structure and function of proteins
・Analyse the rapidly growing body of data on structure-function relationships within GPCRs
・Maintain and present summaries of informatics analyses in a form suitable for broader use
・Keep up to date with Bioinformatics methodologies as applied to drug discovery

The closing date for applications is 14th July 2017.