HeptaresTherapeutics @HeptaresTL 2時間前
We are now seeking an enthusiastic and motivated Biophysical Analyst
ttps://cezanneondemand.intervieweb.it/annunci.php?l=95b2400390af35776000987b1b370889&LAC=rePxIDeWxoT7KshkY1r0KOffbBiX5lE6RexnpP1I4ZY%3D
We are now seeking an enthusiastic and motivated research scientist with experience in the biophysical analysis of membrane proteins, to assist with our drug discovery programmes.
This is an exceptional opportunity to participate in cutting edge science whilst helping to grow an Industry-leading drug discovery company.
The successful candidate will work independently within a project team environment and:
・Perform biophysical analyses (including mass spectrometry, surface plasmon resonance, thermal denaturation) to characterise GPCRs and their interactions with ligands
・Design and implement novel biophysical assays for characterising GPCRs and monitoring ligand binding
・Analyse and evaluate data from biophysical investigations (including estimations of ligand affinities and kinetics of binding) and communicate to project teams
・Assist in the evaluation of new biophysical techniques
HeptaresTherapeutics @HeptaresTL 2時間前
We are currently seeking an experienced Protein Crystallographer
ttps://cezanneondemand.intervieweb.it/annunci.php?l=5dc75a424044305557a6ef3849c2d530&LAC=rePxIDeWxoT7KshkY1r0KOffbBiX5lE6RexnpP1I4ZY%3D
Applicants should have a PhD in protein crystallography or related discipline and be familiar with purification of proteins from recombinant expression systems such as E. coli or baculovirus/insect cells, setting up crystallisation experiments including Lipidic Cubic Phase crystallisation, X-ray data collection, data processing, structure solution and refinement of novel structures and follow on complexes.
Experience working with GPCRs or other membrane proteins would be an advantage Proficiency with single particle cryo-electron microscopy techniques would also be an advantage.
Experience of working in a drug discovery environment where structural studies are used to drive compound design and medicinal chemistry would also be of benefit.
The successful candidate will be expected to work independently and:
・Express and purify GPCRs for structural and biophysical methods;
・Set up and optimise vapour diffusion and LCP crystallisation experiments;
・Collect X-ray diffraction data at synchrotron sources;
・Solve and refine structures; and,
・Present results (written and oral) to internal and external audiences.
次なる飛躍へ。順調な進捗と共に更なる成長の黎明期にて育ちゆく相場。控える材料と共に水準訂正。笑。
予定されていた業績の急成長と共に更なる成長戦略が始動。R&DやPL等の進捗・拡大の加速が始まる。精査。笑。
HeptaresTherapeutics @HeptaresTL 2時間前
We are now seeking an enthusiastic and motivated Biophysical Analyst
ttps://cezanneondemand.intervieweb.it/annunci.php?l=95b2400390af35776000987b1b370889&LAC=rePxIDeWxoT7KshkY1r0KOffbBiX5lE6RexnpP1I4ZY%3D
We are now seeking an enthusiastic and motivated research scientist with experience in the biophysical analysis of membrane proteins, to assist with our drug discovery programmes.
This is an exceptional opportunity to participate in cutting edge science whilst helping to grow an Industry-leading drug discovery company.
The successful candidate will work independently within a project team environment and:
・Perform biophysical analyses (including mass spectrometry, surface plasmon resonance, thermal denaturation) to characterise GPCRs and their interactions with ligands
・Design and implement novel biophysical assays for characterising GPCRs and monitoring ligand binding
・Analyse and evaluate data from biophysical investigations (including estimations of ligand affinities and kinetics of binding) and communicate to project teams
・Assist in the evaluation of new biophysical techniques
HeptaresTherapeutics @HeptaresTL 2時間前
We are currently seeking an experienced Protein Crystallographer
ttps://cezanneondemand.intervieweb.it/annunci.php?l=5dc75a424044305557a6ef3849c2d530&LAC=rePxIDeWxoT7KshkY1r0KOffbBiX5lE6RexnpP1I4ZY%3D
Applicants should have a PhD in protein crystallography or related discipline and be familiar with purification of proteins from recombinant expression systems such as E. coli or baculovirus/insect cells, setting up crystallisation experiments including Lipidic Cubic Phase crystallisation, X-ray data collection, data processing, structure solution and refinement of novel structures and follow on complexes.
Experience working with GPCRs or other membrane proteins would be an advantage Proficiency with single particle cryo-electron microscopy techniques would also be an advantage.
Experience of working in a drug discovery environment where structural studies are used to drive compound design and medicinal chemistry would also be of benefit.
The successful candidate will be expected to work independently and:
・Express and purify GPCRs for structural and biophysical methods;
・Set up and optimise vapour diffusion and LCP crystallisation experiments;
・Collect X-ray diffraction data at synchrotron sources;
・Solve and refine structures; and,
・Present results (written and oral) to internal and external audiences.
成長戦略の順調な進展と加速。笑。次なる展開・進捗も楽しみですね。笑。